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In PCOS granulosa cells, elevated phosphorylation of the pro-apoptotic protein BAX, coupled with suppressed phosphorylation of the anti-apoptotic protein BCL-2, enhances mitochondrial pathway apoptosis, accelerating follicular atresia ( 3.6 Chronic low-grade inflammation Chronic low-grade inflammation have been identified as a central component in the pathogenesis of PCOS, rather than mere accompanying phenomena

2017;67(658):e32935

HMP shunt and cancer: Several studies have investigated the role of the HMP shunt in cancer metabolism

Vitamin C enhances Nanog expression via activation of the JAK/STAT signaling pathway