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5) While some associations have been observed, particularly with gout and renal diseases, evidence from Mendelian randomization studies did not consistently support a causal relationship between elevated serum urate levels and other metabolic or cardiovascular disorders

Male mice were used in all studies and sacrificed by exposure to carbon dioxide at different post-natal weeks: 8 (pre-symptomatic phase), 12 (disease onset), and 18 (late symptomatic phase) 18

[DOI] [PubMed] [Google Scholar] 423.Fehringer M., Vogl T

To view a copy of this licence, visit About this article Cite this article Lei, S., Chen, D., Wu, J

Wang J, Gan C, Retmana IA, Sparidans RW, Li W, Lebre MC, Beijnen JH, Schinkel AH