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Subjective improvements in sleep , energy , and mood may occur within 12 weeks

Hydroxocobalamin also supports cyanide detoxification (beneficial for smokers), as it binds to cyanide and facilitates removal through the kidneys

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The board discussed that measuring serum B12 concentrations to monitor B12 treatment should be decided on a case-by-case basis (for example, when people show new symptoms, to check compliance with oral treatment, and to check whether B12 was absorbed after oral administration)

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