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By preventing the accumulation of toxic lipid intermediates and long-chain acylcarnitines, L-carnitine serves as a potent intracellular antioxidant

For example, insulin, a major hormone in the homeostasis of energy and metabolism, has been implicated in the regulation of miRNA expression (Granjon et al., 2009)

Figure 3 In prostate cancer cells, miR-185 and miR-342 control lipogenesis and cholesterol synthesis by down-modulating the expression of sterol regulatory element binding protein 1 and 2 ( SREBP-1, SREBP-2 ), repressing their responsive genes, including fatty acid synthase ( FASN ) and 3-hydroxy-3-methylglutaryl CoA reductase ( HMGCR

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Individual tolerance varies, and sensitive stomachs may react to sudden changes