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Given the gut-liver axis connection, where intestinal health directly impacts hepatic inflammation, this prebiotic effect may contribute to dandelion's traditional reputation for liver support

First, it acted as a competitive inhibitor of 2-oxoglutarate-dependent dioxygenase (2-OGDD) function, and secondly, glutarate accumulation impaired activity of the pyruvate dehydrogenase complex (PDHc)

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Age-associated changes in the subcellular localization of phosphorylated p38 MAPK in human granulosa cells

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