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TSPO, an outer-mitochondrial-membrane protein widely overexpressed in GBM, enhances resistance to chemotherapy and radiotherapy by restraining the caspase-9/Apaf-1-dependent mitochondrial apoptosis pathway [41]

Notably, MenSCs also secrete multiple angiogenic factors, including VEGF, HGF, angiogenin, and MMP-1, which contribute to both tissue regeneration and immune regulation

It is therefore important to keep in mind the clinical scenario that is being mimicked, i.e., overdose causing injury and recovery versus a severe overdose with injury, limited recovery, and development of acute liver failure

MAFLD and tumors) [85]

Yao M, Yao D, Yamaguchi M, Chida J, Yao D, Kido H