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Induction, and competitive inhibition of cytochrome P-450 enzymes are mechanisms of drug interactions Hepatic synthesis of cytochromes P-450 is induced by certain drugs and other xenobiotic agents: this increases the rate of phase I reactions

In mammals, the key autophagy-regulating proteins, Bcl-2 and Beclin1, are localized to the endoplasmic reticulum and mitochondria [253]

Biochemistry 1995, 34 (34):10844-10850