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Frequently Asked Questions (FAQ) What is Epitalon used for

Neurological symptoms are particularly significant and may include: Paraesthesia (pins and needles) in the hands and feet Numbness or altered sensation in the extremities Difficulty walking or problems with balance and coordination (ataxia) Memory problems and cognitive difficulties Mood changes, including depression and irritability Visual disturbances in severe cases Haematological and general symptoms commonly include: Pale or jaundiced (slightly yellow) skin Glossitis (sore, red, smooth tongue) Mouth ulcers and angular cheilitis (cracks at the corners of the mouth) Breathlessness, particularly on exertion Heart palpitations Headaches and dizziness Gastrointestinal symptoms may present as: Loss of appetite and unintentional weight loss Diarrhoea or constipation General digestive discomfort The severity and combination of symptoms vary considerably between individuals

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The risk of hepatotoxicity is also modulated by background liver disease, obesity or chemotherapy-related fatty liver (as in steatosis), alcohol consumption and genetic mutations in CYP2C9, CYP3A4 and UGT1A1 (213)

Kinetic studies of betaine:homocysteine methyltransferase