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Research 2024 , 7 , 0464

Liposomal systems often have limited drug loading capacity, also may lead to leakage or abnormal release rate, affecting treatment outcomes ( in vivo accumulation, which may increase the risk of pulmonary fibrosis, chronic toxicity, or other adverse outcomes

Increased activity of these phase II detoxification enzymes enhances the bodys ability to manage oxidative stress and inflammatory mediators that contribute to metabolic syndrome (Ngo and Duennwald, 2022)

A synergistic interaction is defined as a combination of stressors that results in a greater effect than the cumulative expected effect from independent exposure 34