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Linear models such as BSLMM, LMMs, GBLUP and PLMM with Generalized Method of Moments Estimator are commonly used for modeling multi-omics data with high predictive accuracy (Roychowdhury et al., 2023)

JAMA 333 (8), 694700 (2025)

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Daver N, Basu S, Garcia-Manero G, Abbas HA, Konopleva M, Kadia TM, DiNardo CD, Borthakur G, Alotaibi AS, Pemmaraju N, Jabbour E, Pierce SA, Brandt M, Takahashi K, Ning J, Kornblau SM , Sasaki K, Yilmaz M, Issa GC, Short NJ, Matthews JA, Flores W, Andreeff M, Cortes JE, Ravandi F, Allison JP, Kantarjian HM, Sharma P

Understanding variants in antioxidant enzyme genes can help provide context on whether you may benefit from higher baseline glutathione support or more frequent dosing adjustments