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2.4 SA--Gal stain SA--Gal staining of cells and tissues was performed using a senescence-associated -galactosidase staining kit (C0602, Beyotime Biotechnology, Shanghai, China), with all procedures strictly following the manufacturers instructions

Methods: MRI measurements of glymphatic function, including choroid plexus (CP) volume, white matter free water (WM FW) fraction, index of diffusivity along the perivascular space (ALPS index), and basal ganglia perivascular space (BG-PVS) volume of CADASIL patients and healthy controls, were calculated and compared

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Tryptophans regulation of ferroptosis involves mechanisms such as the kynurenine pathway (KP) ( Figure 2 ), where host cells generate multiple tryptophan metabolites, including L-kynurenine (L-KYN), kynurenine (KYN), 3-hydroxykynurenine (3-HK), 3-hydroxyanthranilic acid (3-HA), and KYN

Key takeaways Spotting occurs between periods and usually lasts 1-2 days