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A potential future avenue includes long-acting analogues of LEAP2, a native antagonist of the ghrelin receptor, which may reduce food intake by attenuating ghrelin-mediated orexigenic and lipogenic signaling

ACI involves harvesting cartilage, isolating chondrocytes, expanding cells in vitro, and re-implanting over an articular cartilage defect

They detailed lipid metabolism (including a novel FAS) and repression of TOR1, a negative regulator of autophagy, in R

10.1007/978-1-4939-8618-7_17 Methods Mol

Supporting this EMT-promoting role, HGF-induced ROS oxidize the chaperone proteins HSP60 and PDI, thereby activating ERK and enhancing wound-healing and transwell migration