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However, its explicit role in the Y-H transition is yet to be explored [121]

[136] The third stage is being conducted at Pfizer plants in Portage, Michigan [138] (near Kalamazoo) in the United States, and Puurs in Belgium

In a 1995 review of 295 cases of liver transplant for acute liver failure, APAP toxicity was the leading cause for liver transplantation, representing 20% of that cohort