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Another mechanism that has been described as responsible for cisplatin cytotoxicity is the induction of reactive oxygen species (ROS), compounds that interact with macromolecular components, such as lipids, proteins and DNA, generating lesions 5

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Physiological functions of thioredoxin and thioredoxin reductase

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This leads to ferritin degradation, increased labile iron release, elevated lipid peroxidation, and disruption of neuronal membrane integrity

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2.3.1.3 IL-10 IL-10 can inhibit LPS-induced glucose uptake and glycolysis in macrophages and promote OXPHOS (103)

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10.3389/fphar.2019.01684 179 ZhangY.ZhenS.XuH.SunS.WangZ.LiM.et al (2024)

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