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Additional evidence of systemic inflammation effecting the CNS is seen in a mouse model of intraperitoneal LPS injection, which revealed morphological changes in microglia after 3 h, suggestive of an activated state, that persisted up to one week post injection (Yang et al., 2013)

Effects of arginine and ornithine supplementation to a high-protein diet on selected cellular immune variables in adult cats

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Crit Rev Ther Drug Carrier Syst 26(5):427521