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Consistently, Febuxostat at 2.5 mg/kg/day for 12 weeks significantly inhibited plasma XO activity, reduced atherosclerotic plaque formation, and decreased macrophage infiltration in the aortic root, indicating protection against atherosclerosis in ApoE/ mice fed a high-cholesterol diet [187]

Cui K, Qiang Z, Wang R, Ding P, Ren A, Li L, Noor H, Wu X, Sun M, Gao Z (2023) Quinoa ( Chenopodium quinoa Willd.) genome-wide analysis of glutathione s-transferase ( cqgsts ) and transcription factor bHLH family study on their salt tolerance function

Historically, BDZs alone have been shown to be weak reinforcers 30

doi: 10.1073/pnas.91.24.11287, 185

Microglia regulation of central nervous system myelin health and regeneration