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Elevated ROS levels, especially in the early stages of cancer, can contribute to carcinogenesis by promoting genomic instability, mitogenic signaling pathways, and the NF-B pathway, among others [26]

[DOI] [PMC free article] [PubMed] [Google Scholar] 398.Andreani T., Fangueiro J.F., Severino P., de Souza A.L.R., Martins-Gomes C., Fernandes P.M.V., Calpena A.C., Gremio M.P., Souto E.B., Silva A.M