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Together, these case studies demonstrate how conceptual frameworks such as RSM, TTDS, and R2C2 can be effectively translated into practice, delivering tangible benefits across diverse geographic and socio-economic contexts

I am also grateful to the editor and two anonymous referees for thoughtful comments that further helped me to improve the quality of this review

Because it is the most powerful antioxidant in our organism, it is often referred to as the "mother of all antioxidants"

It modulates expression of more than 4,000 human genes, including 84 cancer-suppressing genes

Hypoxic kidney organoids treated with SGLT2i confirmed these protective effects