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Hypoxia-activated prodrugs: paths forward in the era of personalised medicine

Potential mechanisms of action Sleep and GABAergic activity Insomnia and other sleep disorders can have a profound impact on health and quality of life [14]

R.AkbarS.EweidaM.KhnF

Abstract S-nitrosoglutathione (GSNO) is an endogenous donor of nitric oxide (NO), which, at the same time, can act both as a signaling molecule and as a toxic agent, forming reactive nitrogen species