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Description

Molecular pathways driving omeprazole nephrotoxicity

1863 (10 Pt B), 25462553

To this end, we employed a swine model with DM and CKD, and in a comprehensive approach, combined unbiased proteomic assessment of changes in myocardial signaling pathways with direct measurements of cardiac and coronary microvascular function in vivo, mitochondrial function ex vivo, and detailed histological and molecular assessment of myocardial fibrosis and oxidative stress