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These alterations indicate that MELNs exert substantial therapeutic effects on STZ/HFD mice

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A follow-up study investigated the distribution of WDR49-positive astrocytes in other subtypes of FTD and in AD, and showed that WDR49-positive astrocytes are most abundant in FTD-GRN, have a different morphology in FTD with TDP43 versus TAU pathology, and colocalize with senile plaques in AD 226