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Interestingly, a tendency to present liver symptoms of PFIC-related genes in adults before the age of 40 can be observed [9, 42, 71] (Fig

The results need to be confirmed by further studies

Circulation 144(1):719 Hishiya A, Kitazawa T, Takayama S (2010) BAG3 and Hsc70 interact with actin capping protein CapZ to maintain myofibrillar integrity under mechanical stress