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AT immune cells not only promote AT homeostasis, but also change phenotype and increase their number to promote the maintenance and development of local AT inflammation

P2X receptors are non-selective cation channels which are activated by ATP

doi: 10.1038/sj.bjp.0705776

In a dose- and time-dependent manner, hyperactivation of Nrf2 diminished oxidative stress by ameliorating cell apoptosis and improving the redox state of the cell (Song et al