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Mari M, Morales A, Colell A, Garcia-Ruiz C, Fernandez-Checa JC

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(PubMed) McNulty H, McKinley MC, Wilson B, et al

& Shafer, J

Another central feature is the loss of protein balance, especially involving TDP-43, a protein that is abnormally located in the cytoplasm instead of the nucleus in about 97% of ALS cases