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Nature 520(7548):553557 Dunphy G, Flannery SM, Almine JF et al (2018) Non-canonical activation of the DNA sensing adaptor STING by ATM and IFI16 mediates NF-kappaB signaling after nuclear DNA damage

Choi SJ, Lee SN, Kim K, Joo daH, Shin S, Lee J

The methionine-sparing effect of betaine makes methionine more available for protein synthesis, and the choline-sparing effect makes choline more available for lipid metabolism

In contrast, LTF protein degradation that is mediated by neural precursor cell-expressed developmentally downregulated gene 4 (NEDD4)-like E3 ubiquitin protein ligase (NEDD4L) blocks iron-dependent lipid peroxidation during ferroptotic cancer cell death (Wang et al., 2020)

Recently, phytoprostanes in sea buckthorn juices have been discovered, and their quantities are highly connected with the capacity to reduce inflammation through inhibition of the 15-lipoxygenase enzyme ( in vitro hypoglycemic capacity