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When Vitamin C neutralizes a free radical, it "tires out" (oxidizes)

10.1089/acm.2009.0177

Vitamin C, as a water-soluble antioxidant, is important in oral health through neutralising free radicals,d ecreasing oxidative pressure and hindering the release of Vitamin C, as a water-soluble antioxidant, is essential in oral health hrough neutralising free radicals, decreasing oxidative pressure and hindering the release of inflammatory mediators, particularly in decreasing gingival inflammation

Nausea Mild nausea occasionally occurs during the first week of therapy

The elevation of histamine is also an indicator of decreased methylation function as it is inactivated by histamine-methyl transferase