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Administration of luteolin (80 mg/kg/day) resulted in a significant reduction in the activation of p-JNK, p38 MAPK, GFAP, Iba-1, and various inflammatory markers such as p-NF-B p65, tumor necrosis factor-alpha (TNF-), interleukin-1 beta (IL-1), a decrease in pro-apoptotic proteins (including Bax, Caspase-3, Cox-2), a downregulation of BACE-1 and A1-42 concentrations, and an enhancement of synaptic markers (namely PSD-95, SNAP-25)

therefore, our conclusions focus primarily on temperature-dependent regulation of T-cell motility and associated metabolic and transcriptional changes

A small heat shock protein (sHSP-DQ 986457) was identified as a shared gene between T

BPC-157 exhibits promising anti-cancer properties by suppressing tumor growth, inhibiting angiogenesis, modulating the immune system, and protecting against chemotherapy-induced toxicity

Neuron 49(6):797804