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Hypoxic conditions result in a more aggressive phenotype of cancer cells, likely due to hypoxia-induced changes in gene expression and subsequent proteomic alterations [47]

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To avoid that step, stabilized yeast cream is also available thanks to the addition of xanthan gum

[5] Administering 100,000 IU intramuscularly establishes a high-capacity depot that may correct deficiency more predictably than oral dosing in malabsorption syndromes and maintains adequate circulating vitamin D over two to three months, an approach often referred to as Stoss therapy in endocrinology