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Also, Red rice bran extract exhibited a potent endothelium-dependent vasorelaxant effect via activation of eNOS and subsequent NO production

Bain, M., Hart, B., Cliff, K., Ruehl, W

The previous interactions contribute to the activation of the peripheral immune system and primes CNS microglia, creating a neuroinflammatory environment that aggravate behavioral deficits (Manda et al., 2012