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Orphan Drugs 4 , 719728 (2016)

[] There is controversy about the liver to the skeletal muscle crosstalk in patients with comorbidity of NAFLD and sarcopenia, as that NAFLD and sarcopenia share many complex interplaying mechanisms, including insulin resistance and myostatin and adiponectin homeostasis, which make it difficult to determine the actual cause, therefore, identifying whether sarcopenia is a cause, consequence, both, or neither of fatty liver is challenging

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doi: 10.1017/S0022029919000682 18 TommasoniCFioreELisuzzoAGianesellaM

1.11.2 NEUROLOGICAL DISEASES It has been observed that cranium-encephalic traumatisms cause cerebral injury or spinal medulla