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Additional functional gene enrichment analysis revealed that, at high altitudes, gut microbiota exhibit an increased potential for utilizing CO 2 and oxaloacetate in the synthesis of energy substrates such as acetyl coenzyme A and pyruvate, respectively, and in the conversion of acetyl coenzyme A into acetate (Zhao et al., 2023b)

On the other hand, LC-MS boasts high sensitivity and selectivity, making it particularly advantageous for detecting trace levels of carnitines in samples