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( b ) EtOH levels in liver, serum, bile samples from Mdr2 KO mice ( Mdr2 / ) (n = 5) and control WT mice (n = 5) 3 h post ethanol (5 g/kg) gavage

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When MPO is secreted into the extracellular space, it converts hydroperoxides into free radicals, which then causes LPO, oxidative stress development, and tissue injury [91]