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The New Guinean kindreds particular mutation was the first group described

Specifically, only one perioperative high-dose NAC study (150 mg/kg preoperative followed by 50 mg/kg for 6 h) [52] found a significant reduction in perioperative AKI, and all other high-dose papers with a later dosing period trended toward AKI reduction, even though not all reached statistical significance

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It has been reported that ginseng may reduce the energy harvesting of rats by inhibiting pancreatic lipase activity in the exogenous pathways of lipid metabolism (Lee et al., 2013)