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Additionally, certain inhibitors, such as KW-2449 and Necrostatin-1, have been found to suppress both cell death pathways simultaneously, suggesting that they may share common regulatory mechanisms

Lango R, Smolenski RT, Narkiewicz M, Suchorzewska J, Lysiak-Szydlowska W (2001) Influence of L-Carnitine and its derivatives on myocardial metabolism and function in ischemic heart disease and during cardiopulmonary bypass

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The Rise of Antioxidants [edit] During the transition from aerobic to anaerobic conditions, phylogenetic investigations suggest that SODs are ancient molecules, which were likely selected for before the GOE