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Metanx alleviates multiple manifestations of peripheral neuropathy and increases intraepidermal nerve fiber density in Zucker diabetic fatty rats

This was achieved by inhibiting bone resorption through an increase in the OPG/RANKL ratio and promoting bone formation by enhancing the expression of osteoblast-specific transcription factors

Wrist Circles: Slowly rotate wrist in circles, 10 each direction, 3 times daily Forearm Stretch: Extend arm, gently pull fingers back, hold 30 seconds Ball Squeeze (light): Gentle squeezes with soft stress ball, 10 reps, 2 times daily Supination/Pronation: Rotate forearm palm-up to palm-down, 15 reps Progressive Loading Phase (Weeks 3-6) As pain decreases and function improves, gradually introduce more challenging exercises