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Virology 391 , 249256 (2009)

However, the therapeutic index of doxorubicin is undermined by dose-dependent cardiotoxicity, which may be a function of futile redox cycling

Furthermore, we elucidated the key mechanisms and pathways by which this system promotes hair growth

The Fenton Reaction: Free iron can be involved in the formation of free radicals by the superoxide-driven Fenton reaction, leading to glutathione depletion, oxidative stress, degradation of protein and nucleic acids, and lipid peroxidation

These conflicting findings could be attributed to variations in the source of GPX3, whether derived primarily from the kidneys or locally expressed and secreted by bronchial epithelial cells