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doi: 10.1038/S41590-021-01009-W

In their efforts to develop a series of StAMPs with limited nonspecific membrane toxicity based on Mag2, Mourtada and co-workers [87] discovered that when the hydrocarbon staple was positioned within one of the high hydrophobicity patches on the AMPs helical, the hemolytic activity remained similar to the native AMP

otherwise, samples must be stored at 20C (for up to 1 month) or 80C (for up to 2 months) to avoid loss of bioactivity and contamination

For aging people, impaired intestinal function, including mucosal barrier damage and motility disorders, is a significant cause of constipation (27)