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and (6) 4Fe-4S coordinated by four Cys residues with one Cys cross-bridging a siroheme (Figure 1) (Johnson et al., Figure 1 The plant-type ferredoxin (Fd) is a classic 2Fe-2S protein

For example, certain natural compounds have been found to enhance the effectiveness of chemotherapy for lung cancer by inducing ferroptosis, offering a new solution to chemotherapy resistance