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They can influence hormone production, immune responses, and cell growth and repair [3]

Key considerations when switching: Allow a washout period based on tirzepatide half-life Start retatrutide at the standard 1mg initiation dose regardless of previous tirzepatide dose Expect renewed GI side effects as the glucagon receptor is a new stimulus Monitor heart rate more carefully during the initial escalation period When tirzepatide is the better choice Tirzepatide remains the superior option in several specific situations

Exercise is essential to maintain muscle strength and flexibility, control weight, and improve overall well-being in people with FM, which can also change the levels of endorphins and serotonin, which affect pain threshold, mood, and anxiety [78]

J Biochem Mol Toxicol 34:e22439

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