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Astrocyte degeneration can be induced/caused by various factors, including injury, disease, aging, or toxicant exposure

J Korean Med Obes Res 17:7786 Iyer J, Singh MD, Jensen M, Patel P, Pizzo L, Huber E, Koerselman H, Weiner AT, Lepanto P, Vadodaria K (2018) Pervasive genetic interactions modulate neurodevelopmental defects of the autism-associated 16p11