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The varying effects of HbS on infection suggest that its protective role against malaria may be related to controlling P.f hyperparasitemia [21]

Collagen Production : Vitamin C is essential for the synthesis of collagen, a protein that contributes to the structure and health of skin, bones, blood vessels, and connective tissues

MFC-MSNs can be used as drug delivery vehicles to enhance therapeutic effects through sustained release of methotrexate (MTX)

This finding is intriguing because human glutathione synthetase deficiency, a heritable amino acid metabolism disorder, also leads to hyperaccumulation of pyroglutamic acid resulting in high anion gap metabolic acidosis a form of acidosis defined by acid accumulation and low pH of the blood 48

The observation that BH4 synthesis is dramatically induced in mammalian cells by cytokines puzzled researchers for many years, as there was no known enzyme that was both inducible and BH4-dependent