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and Jin et al., showed that high concentrations of HNE (30-200 M) increased NLRP3 mRNA expression, IL-1, and IL-18 secretion in human ARPE-19 cells after LPS stimulation (60, 61)

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Macrolipophagy mediated by Rab7 induces autophagic degradation of lipid droplets by LC3-II-positive membranes via lysosomal transportation and degradation

Bone sections were stained for Perls Prussian Blue (Abcam, ab150674) to detect Fe deposits, following the manufacturers protocol [12]