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Intriguingly, supplementation with mitochondria-targeted TEMPO (mitoTEMPO), which accumulates in active mitochondria where the reduction of its active nitroxide to hydroxylamine is mainly mediated by ubiquinol 35 , also significantly rescued survival upon LDHB silencing (Fig

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Lancet Neurol 13(10):10451060 Weisgraber KH (1994) Apolipoprotein E: structure-function relationships

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: L- L- ,

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4.1.3 In vitro human studies In vitro studies focus mainly on the antioxidant activity of melatonin and its relationship with the production of gonads

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