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[DOI] [PubMed] [Google Scholar] 58.DeBruyne JP, Weaver DR, Reppert SM

HIF-1 activation may also lead to increased glucose uptake and induced aerobic glycolysis in the infected cells (Semenza, 2011)

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The dose depends on the formulation: 1.4 mg daily for Egrifta SV, 1.28 mg daily for Egrifta WR, or 2 mg daily for research vials (matching the original Phase III trial dose)