glutathione and glutathione-s-transferase in detoxification mechanisms

glutathione and glutathione-s-transferase in detoxification mechanisms Roles for transferases plant secondary metabolism Glutathione transferases as mediators of

Name: glutathione and glutathione-s-transferase in detoxification mechanisms Roles for transferases plant secondary metabolism Glutathione transferases as mediators of
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Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death Cell Death & Differentiation Glutathione S transferase : a potential role in antitumor therapy DDDT Dove Medical Press The role of glutathione S transferases in human disease pathogenesis and their current inhibitors PMC Glutathione transferases: substrates, inihibitors and pro drugs in cancer and neurodegenerative diseases Oncogenesis RCSB PDB 1AQW: GLUTATHIONE S TRANSFERASE IN COMPLEX WITH GLUTATHIONE

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doi: 10.1016/j.ejphar.2020.173090 67 SusserLINguyenM-AGeoffrionMEmertonCOuimetMKhachoMet al

These phytochemicals inhibit NF-B/STAT3 activation, which suppresses tumor growth and metastasis in certain models of breast and colorectal carcinomas

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Indeed, NMDA receptor inhibition in the prefrontal cortex increases extracellular glutamate that acts on AMPA and kainate receptors, which in turn stimulate dopamine release in the prefrontal cortex and striatum ([8] and references therein)