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Stomach acid tends to decrease with age, which makes it harder to extract B12 from food

Risks of Worsening Optic Nerve Damage Theres a concern with Vitamin B12 for LHON patients

Physicians should consider that vitamin B12 levels between 200 and 300 pg/mL (148 to 221 pmol/L) are considered borderline, suggesting a possible deficiency, and further testing with methylmalonic acid (MMA) and homocysteine may be necessary

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