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At the opposite extreme, the odorless class exhibits the lowest mean LogP ( 1.1) with outliers descending below 10

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The main causes of mitochondrial swelling are collectively known as direct inner membrane damage induced by oxidative stress and calcium overload in the mitochondrial matrix, forcing an increase in membrane pore permeability and a consequent alteration of osmotic pressure between the outer and inner membranes [7, 8]

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Drugs 18 , 331 (2020)