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Experimental studies have explored potential interactions with multiple signaling systems and regulatory pathways, but no single receptor target has achieved broad consensus

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Normally sequestered in cytoplasm by Keap1

DSIP has been studied for various potential physiological roles, including: Stress response and adaptation Pain modulation Immune system regulation Antioxidant properties Effects on endocrine function DSIP has been investigated for potential applications in sleep disorders, pain management, and substance withdrawal syndromes