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Together, these results suggest that NK cells in ATB patients display an exhausted phenotype characterized by altered transcriptional profiling, impaired cytotoxic activity, increased apoptosis, as well as compromised anti-Mtb capacity

*Disclaimer: These statements have not been evaluated by Health Canada or the FDA

When the body is in a state of hypoxia, infection, intense exercise, etc, and the cells demand for ATP increases, pyruvate and NADH tends to be directly catalyzed by lactate dehydrogenase (LDH) to produce lactate, rather than entering the mitochondria to participate in the tricarboxylic acid cycle (TCA)

Is there a common molecular pathway for addiction

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