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HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations

doi: 10.1016/j.molmet.2024.102058 43 PillonNJSmithJABAlmPSChibalinAVAlhusenJArnerEet al

Ultimately, these distinct gut microbiome signatures hold great potential as non-invasive biomarkers for diagnosis, prognosis, and therapeutic efficacy assessment, establishing intestinal niche modulation as a viable synergistic strategy with existing hepatology therapies